Pre- and posthatch developmental changes in hypothalamic thyrotropin-releasing hormone and somatostatin concentrations and in circulating growth hormone and thyrotropin levels in the chicken

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Pre- and posthatch developmental changes in hypothalamic thyrotropin-releasing hormone and somatostatin concentrations and in circulating growth hormone and thyrotropin levels in the chicken.

Thyrotropin-releasing hormone (TRH) and somatostatin (SRIH) concentrations were determined by RIA during both embryonic development and posthatch growth of the chicken. Both TRH and SRIH were already detectable in hypothalami of 14-day-old embryos (E14). Towards the end of incubation, hypothalamic TRH levels increased progressively, followed by a further increase in newly hatched fowl. SRIH con...

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The Therapeutic Effect of Thyrotropin Releasing Hormone in Amyotrophic Sclerosis

Although the issue has not yet been fully resolved, there is reason to believe that TRI-I may have a trophic effect on the normal motoneuron and may transien­ tly improve the neurologic deficit in ALS. Since ALS is not a simple TRI-I deficiency disease, this improvement probably occurs via a secondary mecha -nism-possibly another neurotransmitter. It is uncertain at this time whether this effec...

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Bovine serum hormone concentrations after thyroprotein and thyrotropin releasing hormone.

Twenty-four Holstein heifers were assigned randomly to one of four t reatment groups to be given: 1) thyroprote in (TP) for 6 days; 2) casein for 6 days; 3) TP for 27 days; or 4) casein for 27 days. Thyrotropin releasing hormone (TRH, 33.3 /~g/100 kg BW) was given at 1030 and 1330 hr on day 6 or 33 to heifers treated for 6 or 27 days, respectively. Prior to TRH treatment , serum thyroxine (T4) ...

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Assessment of thyrotropin-releasing hormone and thyrotropin reserve in man.

Endogenous thyrotropin-releasing hormone (TRH) reserve and pituitary thyrotropin (TSH) reserve were assessed in four normal subjects, three patients post-cryohypophysectomy, one patient with a hypothalamic lesion secondary to trauma, and four patients with Sheehan's syndrome. TSH reserve was determined by the immunoassayable TSH response to 500 mug TRH given i.v. (TRH stimulation test). TRH res...

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ژورنال

عنوان ژورنال: Journal of Endocrinology

سال: 1998

ISSN: 0022-0795,1479-6805

DOI: 10.1677/joe.0.1590219